About   Help   FAQ
Symbol
Name
ID 		Nos1
nitric oxide synthase 1, neuronal
MGI:97360
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hyposmia
Spasticity
Bradykinesia
Tremor
Depression
Anxiety
Panic attack
Hallucinations
Apathy
Reduced social reciprocity
Impulsivity
Agitation
Restless legs
Cognitive impairment
Dementia
Frontal lobe dementia
Short attention span
Insomnia
Hyperreflexia
Dyskinesia
Dystonia
Gait imbalance
Postural instability
Abnormal autonomic nervous system physiology
Disease(s) Associated with NOS1
cystic fibrosis
Parkinson's disease

Mouse Phenotypes
nervous system phenotype
abnormal seizure response to inducing agent
abnormal blood-brain barrier function
decreased susceptibility to neuronal excitotoxicity
abnormal neuron differentiation
slow Wallerian degeneration
decreased susceptibility to ischemic brain injury
decreased cerebral infarct size
abnormal brain morphology
abnormal motor neuron morphology
abnormal dendrite morphology
abnormal nervous system physiology
abnormal hypothalamus secretion
abnormal brain wave pattern
abnormal peripheral nervous system regeneration
delayed peripheral nervous system regeneration
abnormal long-term potentiation
absent long-term depression
decreased synaptic glutamate release
Availability Mouse Genotype
Nos1tm1Enik/Nos1tm1Enik
Nos1tm1Plh/Nos1tm1Plh *
Nos1tm2Plh/Nos1tm2Plh
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory